I use bravecto and interceptor plus for my two. Frontline stopped working in my area. Last year is when I started bravecto, Cleo was tick and flea free. Never had a problem. Cleo and Relic both are on it now. My vet recommended it for us since we choose to not use advantix, advantage multi, or revolution since it can cause a reaction with collies or any other herding breed.
Mine is on the exact same now, and last year he was tick and flea free as well. And we actually live in a forest adjacent to a large regional park. We've got deer, foxes galore, mice, squirrels, chipmonks, mices, rabbits, etc, etc.
I really like the Serestro collar we used for a year and a half until I found out its active ingredient was statistically significant in studies of canine cancers. Gotta find that cite.
And, I have been buying the 100# size and breaking it in 2 to reduce the cost.
I know there is a belief that you shouldn't do that because you can't be sure all the ingredients are mixed in the same proportions and thus might be over/under-dosing by breaking the tablet.
Unfortunately, I've been inside bio-tech company production facilities, and everything from tomato paste to consumer goods conglomerates, and the fact is that prior to actually extruding out pills, shampoo, tomato paste, laxitives, capsules, etc, everything is mixed, and in fact kept mixing until it hits the tube or ejection mold and is dolloped out.
In this instance, both ingredients are granualized to the same size so as to prevent uneven distribution through simple settling. In fact, if they weren't, they wouldn't be able to accurately measure anything, nor guarantee how much of which ingredient was actually getting into the pill or capsule.
If you're curious, look up compounding, and its quite involved for the few pharmacies that still do it.
Not trying to rant, however really hate to see people paying a lot more than they could.
EDIT- Just saw the comment about skin permeability.
I'm just gonna leave this here.
https://personalcaretruth.com/2011/01/the-impermeable-facts-of-skin-penetration-and-absorption/
The fact that we can't just wipe on aspirin, tylenol or ibuprofin among others should make the point that the skin is not a freeway into the body.
Actually, the whole reason for 'skin' is to prevent such from happening.
The whole follicles, lipids, etc are fascinating. While the GBM is something to investigate, I'm not going to jump on the bandwagon of assuming Corporate Scientists are fully aware of some major potential for poisoning of our companions and knowingly keeping quiet. Just like Big Tobacco, anything less than Due Diligence could quite easily be the end of their company vs a voluntary recall.
and "animals"have to bite the dog before it works -as Bravecto
