Justicemom
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I personally do not give lepto. It has nothing to do with MDR1.
The vaccine is against 4 of around 200(I think 20 are important in dogs) serovars of lepto. Immunity is short lived around 9-10 months and it starts to wane so you need to rebooster yearly. We do see a lot of vaccine reactions to this disease and in some lines there maybe genetics predisposition. 2 of my dogs(Justice and Ember) have known genetic predisposition(known family members with reactions) to vaccine reactions. Ember has had a vaccine reaction herself to Lyme vx. So risk to benefit does not support giving it. .
That being said it is a zoonosis and can potentially be fatal if the pet is affected. You really need to look at your lifestyle and the dogs living conditions, a city dog has a low risk compared to rural country or lake country. I would also touch based with the breeder and discuss why she recommends against it. Possibly ask the vet if the serovars in the vaccine are those seen in your areas. We had a study done in my area years ago and interesting the top 3 serovars coming up on titers(meaning exposure) were not ones that can be vaccine for. This is another reason I elected not to vaccinated for it.
Interestingly I was just at a Dr. Dodds seminar today and she was talking about non-core vaccines and she listed Lepto yes? and suggested the same reasons I stated. Which surprised me because I was assuming it would be a generic no. Dr. Schultz talks tomorrow and I will let you know if he says anything about Lepto.
The vaccine is against 4 of around 200(I think 20 are important in dogs) serovars of lepto. Immunity is short lived around 9-10 months and it starts to wane so you need to rebooster yearly. We do see a lot of vaccine reactions to this disease and in some lines there maybe genetics predisposition. 2 of my dogs(Justice and Ember) have known genetic predisposition(known family members with reactions) to vaccine reactions. Ember has had a vaccine reaction herself to Lyme vx. So risk to benefit does not support giving it. .
That being said it is a zoonosis and can potentially be fatal if the pet is affected. You really need to look at your lifestyle and the dogs living conditions, a city dog has a low risk compared to rural country or lake country. I would also touch based with the breeder and discuss why she recommends against it. Possibly ask the vet if the serovars in the vaccine are those seen in your areas. We had a study done in my area years ago and interesting the top 3 serovars coming up on titers(meaning exposure) were not ones that can be vaccine for. This is another reason I elected not to vaccinated for it.
Interestingly I was just at a Dr. Dodds seminar today and she was talking about non-core vaccines and she listed Lepto yes? and suggested the same reasons I stated. Which surprised me because I was assuming it would be a generic no. Dr. Schultz talks tomorrow and I will let you know if he says anything about Lepto.