Trifexis

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SheltieFan

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Hi,
Has anyone given their sheltie Trifexis? It would be instead of Interceptor and Comfortis that we presently give him. Our vet said it was safe for shelties, but on the Trifexis website it states:

"Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets."

I was wondering what others thought about this medicine.
Thanks!
 
The label is basically saying that large doses of ivermectin (more than is in a Heartgard pill) reacts negatively with the active ingredient in Comfortis.

I use Interceptor and when I give them Comfortis, it's because I have seen evidence of fleas. I try to give it 7-10 days after Interceptor. I don't give them Comfortis every month so I'd rather not buy the combo when they don't always need one of the ingredients.
 
My vet suggested this to me today versus Sentinel. Is there a reason to change? It looks like cost is about $40 (for 6 pills on Drs. Foster and Smith). I mean, it's expensive enough, why do I want to pay more?

I mean, I already have my dog on Sentinel, Advantix, and Capstar as needed. Do I really need Trifexis?
 
Update on Trifexis

My Sadie is 15 weeks now and the vet gave me Trifexis. Is this really for heartworms and fleas?
Have any of you used it?
It's really expensive. $20 for one pill each month.
Not sure I want to use it.
What would I use in place of this pill?

Thanks for any help
 
We had one of our Shelties at the Vet for a well visit the other day.... we got on the subject of Sentinel and Interceptor... our Vet stated that the Trifexis was the generic form of Sentinel. More importantly, he also told us the makers of Sentinel and Interceptor had "quality control" issues at the factory a couple of months ago and those products haven't been manufactured for probably 3-4 months and still aren't being made. The supply of those is going to dwindle and might cost more as the supply lessens. Since Trifexis is the generic form of Sentinel, the cost should be a little less. In fact, I received an email from my Vet with a link for some $$$ off a purchase.

We have the utmost faith in our Vet. So, once our supply of Sentinel is gone, we'll be switching to the Trifexis. I guess we'll see then. I haven't attempted to verify the claim made about the quality control issue. But, I don't think my Vet would knowingly steer us wrong.
 
Just to go a little further with my statement in the above post, I refer to a couple of pieces of info... THIS from Vet Depot and THIS is the FDA's report of the plant that manufactures Interceptor, Sentinel and other meds.
The only difference I see between Sentinel and Trifexis are the flea inhibitors. The milbemycin oxime is common in both for the parasite control, while spinosad is used in Trifexis and lufenuron in Sentinel to control fleas. Of course, the manufacturers are different.
 
ClantyreSheltie said:
I dont mess with what works, and Interceptor works. I dont do those combo deals.
Click to expand...

I am of the same exact train of thought. Also our rescue recommends Interceptor above all others for our shelties. Thank you Callie's Mom, for the heads up about Comfortis and spanning out seven-ten days from Interceptor meds.




Kate
 
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We started using Trifexis this year too and I've been really happy with it. No adverse reactions and no problems with fleas since using it. Plus its really convenient that it treats heartworm too.

My vet too recommended giving it to them with food.

My vet is against the use of the majority of the topicals, theres only a select few that she recommends. Trifexis being one of them. She feels that the chemicals in many topicals are just too toxic.

I did do some research online about Trifexis. The fact of the matter is, there are horror stories and the potential for an adverse reaction with every drug. You just have to look at your dog/situation and weigh out your options.

What I found in my reading was that the 'reactions' that people documented were exactly what the drug warns about in its facts sheet and almost never resulted in deaths. Deaths only seemed to occur in dogs that were not well in the first place and the drug company did not experience any deaths in their testing, unlike with some other topicals.

I also noticed that people were still giving their dogs the drug after they'd experienced an adverse reaction, which is just not using common sense.
 
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